Basic Information

Aceso App/ Crohn's disease suite / results for "Greece_1_IonXpress_026_DADC06277_TSVC.vcf"

  • Job Title : 19Jan2022_06_17_48#AUA20525
  • Program : Chronos WebServer
  • Database : Aceso Application CD Database
  • Molecule Type : STRING | VCF FILE
  • Input Data : 37023
  • Accepted Input Data : 35759
  • Rejected Input Data : 1264
  • Identified SNPs : 57
  • Date of Analysis : 19Jan2022

SNPs Analysis Results for SLE

Strong-associated SNPs

High-associated SNPs

Associated SNPs


SNPChromosomePositionRefGenomeMutationsGeneVariantTypeDiseaseLitVarClass
rs12103 chr1 1312114 (GRCh38.p13) T>A / T>C / T>G INTS11 Synonymous Variant||MIR6727|500B Downstream Variant||PUSL1|500B Downstream Variant CrohnDisease=3
Colitis_Ulcerative=3
InflammatoryBowelDiseases=2
Isobutyryl_CoADehydrogenaseDeficiency=2
Schizophrenia=1
rs12103 C
rs1061622 chr1 12192898 (GRCh38.p13) T>G TNFRSF1B Initiator Codon Variant Arthritis_Rheumatoid=41
Neoplasms=38
Carcinoma_Non_Small_CellLung=27
DepressiveDisorder=27
LupusErythematosus_Systemic=25
C
rs7530511 chr1 67219704 (GRCh38.p13) T>A / T>C IL23R Missense Variant Psoriasis=24
CrohnDisease=11
Colitis_Ulcerative=9
CerebralHemorrhage=5
Isobutyryl_CoADehydrogenaseDeficiency=5
rs7530511 B
rs2476601 chr1 113834946 (GRCh38.p13) A>G / A>T PTPN22 Missense Variant||AP4B1-AS1|Intron Variant Arthritis_Rheumatoid=914
AutoimmuneDiseases=646
LupusErythematosus_Systemic=617
DiabetesMellitus=366
DiabetesMellitus_Type1=175
C
rs3737240 chr1 150510879 (GRCh38.p13) C>A / C>T ECM1 Missense Variant Colitis_Ulcerative=4
CrohnDisease=3
InflammatoryBowelDiseases=2
Isobutyryl_CoADehydrogenaseDeficiency=1
rs3737240 C
rs13294 chr1 150512511 (GRCh38.p13) G>A / G>T ECM1 Missense Variant CrohnDisease=3
Colitis_Ulcerative=3
InflammatoryBowelDiseases=2
Isobutyryl_CoADehydrogenaseDeficiency=1
rs13294 C
rs2274910 chr1 160882256 (GRCh38.p13) T>A / T>C ITLN1 Intron Variant InflammatoryBowelDiseases=4
CrohnDisease=4
Colitis_Ulcerative=3
ZellwegerSyndrome=2
Arthritis_Rheumatoid=2
rs2274910 C
rs5744174 chr1 223111186 (GRCh38.p13) A>G TLR5 Missense Variant Bronchiolitis=27
HelicobacterInfections=11
Asthma=9
HepatitisB=8
Stroke=6
C
rs11706052 chr3 49026677 (GRCh38.p13) A>G IMPDH2 Intron Variant GraftVsHostDisease=3
Neutropenia=3
BoneMarrowDiseases=3
KidneyDiseases=2
CytomegalovirusInfections=1
C
rs9858542 chr3 49664550 (GRCh38.p13) G>A BSN Synonymous Variant Arthritis_Rheumatoid=4
CrohnDisease=3
Isobutyryl_CoADehydrogenaseDeficiency=2
Colitis_Ulcerative=2
Schizophrenia=2
rs9858542 C
rs3197999 chr3 49684099 (GRCh38.p13) G>A / G>T MST1 Missense Variant||APEH|500B Downstream Variant CrohnDisease=22
InflammatoryBowelDiseases=16
Isobutyryl_CoADehydrogenaseDeficiency=9
Colitis_Ulcerative=8
LupusErythematosus_Systemic=6
rs3197999 A
rs2276707 chr3 119815306 (GRCh38.p13) C>G / C>T NR1I2 Intron Variant Neoplasms=5
BreastNeoplasms=5
Colitis_Ulcerative=3
ColorectalNeoplasms=3
LungNeoplasms=3
C
rs30187 chr5 96788627 (GRCh38.p13) T>A / T>C ERAP1 Missense Variant Spondylitis_Ankylosing=38
Psoriasis=31
BehcetSyndrome=29
MultipleSclerosis=23
Hypertension=16
C
rs2248374 chr5 96900192 (GRCh38.p13) A>G ERAP2 Non Coding Transcript Variant||ERAP1|Intron Variant Carcinoma_Non_Small_CellLung=6
Psoriasis=5
Spondylitis_Ankylosing=4
Arthritis_Psoriatic=2
CrohnDisease=2
rs2248374 C
rs272893 chr5 132327369 (GRCh38.p13) T>C / T>G SLC22A4 Missense Variant||MIR3936HG|Intron Variant SandhoffDisease=11
DiabetesMellitus_Type2=4
DiabetesMellitus=4
Isobutyryl_CoADehydrogenaseDeficiency=1
IntervertebralDiscDegeneration=1
C
rs180802994 chr5 150848174 (GRCh38.p13) G>A / G>C / G>T IRGM Missense Variant CrohnDisease=4
Colitis_Ulcerative=2
rs180802994 C
rs72553867 chr5 150848404 (GRCh38.p13) C>A / C>T IRGM Missense Variant CrohnDisease=4
LupusErythematosus_Systemic=1
Charcot_Marie_ToothDisease_Type1D=1
Tuberculosis=1
GeneticDiseases_Inborn=1
rs72553867 C
rs10065172 chr5 150848436 (GRCh38.p13) C>A / C>T IRGM Missense Variant CrohnDisease=18
GaucherDisease=14
Tuberculosis=6
Hypertension=5
Tuberculosis_Meningeal=4
rs10065172 A
rs3208181 chr6 32745253 (GRCh38.p13) T>C HLA-DQA2 Synonymous Variant C
rs2075820 chr7 30452621 (GRCh38.p13) C>T NOD1 Missense Variant CrohnDisease=11
HelicobacterInfections=5
ColorectalNeoplasms=4
Asthma=2
Inflammation=2
rs2075820 B
rs2072183 chr7 44539581 (GRCh38.p13) G>A / G>C / G>T NPC1L1 Synonymous Variant Gallstones=12
AdenomatousPolyposisColi=10
Dyslipidemias=6
CoronaryDisease=3
SandhoffDisease=2
C
rs1045642 chr7 87509329 (GRCh38.p13) A>C / A>G / A>T ABCB1 Missense Variant Epilepsy=413
BreastNeoplasms=355
Neoplasms=224
Drug_RelatedSideEffectsAndAdverseReactions=198
ColorectalNeoplasms=174
C
rs1128503 chr7 87550285 (GRCh38.p13) A>G ABCB1 Synonymous Variant Drug_RelatedSideEffectsAndAdverseReactions=76
Neoplasms=64
BreastNeoplasms=52
Epilepsy=49
AtaxiaTelangiectasia=45
C
rs1800972 chr8 6877901 (GRCh38.p13) C>G / C>T DEFB1 5 Prime UTR Variant Gastritis=13
DiabetesMellitus=12
Periodontitis=11
ChronicPeriodontitis=8
HIVInfections=8
C
rs1799946 chr8 6877909 (GRCh38.p13) C>T DEFB1 5 Prime UTR Variant Gastritis=18
Isobutyryl_CoADehydrogenaseDeficiency=9
Periodontitis=7
HepatolenticularDegeneration=7
HIVInfections=6
C
rs3810936 chr9 114790605 (GRCh38.p13) T>C TNFSF15 Synonymous Variant LupusErythematosus_Systemic=9
Isobutyryl_CoADehydrogenaseDeficiency=6
GravesDisease=6
CrohnDisease=5
GravesOphthalmopathy=5
rs3810936 B
rs10781499 chr9 136371953 (GRCh38.p13) G>A CARD9 Synonymous Variant Isobutyryl_CoADehydrogenaseDeficiency=7
Tuberculosis_Pulmonary=6
CrohnDisease=5
Colitis_Ulcerative=5
LupusErythematosus_Systemic=3
rs10781499 C
rs4077515 chr9 136372044 (GRCh38.p13) C>A / C>T CARD9 Missense Variant CrohnDisease=15
Colitis_Ulcerative=14
LupusErythematosus_Systemic=9
DiabetesMellitus=7
LiverCirrhosis_Biliary=7
rs4077515 C
rs2236379 chr10 6485181 (GRCh38.p13) G>A / G>C PRKCQ Missense Variant CrohnDisease=1 rs2236379 C
rs1042058 chr10 30439172 (GRCh38.p13) T>C MAP3K8 Synonymous Variant CrohnDisease=10
Keratitis_Dendritic=1
Colitis=1
Isobutyryl_CoADehydrogenaseDeficiency=1
rs1042058 B
rs7076156 chr10 62655424 (GRCh38.p13) A>C / A>G / A>T LOC105378327 Splice Donor Variant Nephrolithiasis=8
DiabetesMellitus=7
AutoimmuneDiseases=4
AlzheimerDisease=4
CrohnDisease=4
rs7076156 C
rs2289311 chr10 77805897 (GRCh38.p13) G>A / G>C / G>T DLG5 Intron Variant InflammatoryBowelDiseases=1
Neoplasms=1
Necrosis=1
FragileXSyndrome=1
Isobutyryl_CoADehydrogenaseDeficiency=1
C
rs1248696 chr10 77856847 (GRCh38.p13) T>A / T>C / T>G DLG5 Missense Variant Isobutyryl_CoADehydrogenaseDeficiency=35
CrohnDisease=31
InflammatoryBowelDiseases=31
Colitis_Ulcerative=5
CeliacDisease=2
rs1248696 A
rs2243639 chr10 79941966 (GRCh38.p13) T>C / T>G SFTPD Missense Variant Isobutyryl_CoADehydrogenaseDeficiency=12
PulmonaryDisease_ChronicObstructive=9
Colitis_Ulcerative=3
BronchopulmonaryDysplasia=3
InflammatoryBowelDiseases=2
C
rs1051992 chr11 6319476 (GRCh38.p13) A>G / A>T CAVIN3 Missense Variant||LOC101927825|Non Coding Transcript Variant CrohnDisease=2
Colitis_Ulcerative=2
EndometrialNeoplasms=2
AdenomatousPolyposisColi=1
rs1051992 C
rs767455 chr12 6341779 (GRCh38.p13) T>C TNFRSF1A Synonymous Variant Arthritis_Rheumatoid=10
Neoplasms=7
BreastNeoplasms=7
Infections=5
HeartDiseases=4
C
rs3764021 chr12 9681032 (GRCh38.p13) C>G / C>T CLEC2D Missense Variant Colitis_Ulcerative=5
LiverCirrhosis_Biliary=5
CrohnDisease=3
DiabetesMellitus_Type2=3
DiabetesMellitus=3
rs3764021 C
rs3761863 chr12 40364850 (GRCh38.p13) T>C LRRK2 Missense Variant||LOC105369736|Intron Variant ParkinsonDisease=11
CrohnDisease=7
AlzheimerDisease=5
SupranuclearPalsy_Progressive=4
ZAP70Deficiency=4
rs3761863 B
rs2228226 chr12 57472038 (GRCh38.p13) G>C GLI1 Missense Variant||ARHGAP9|500B Downstream Variant InflammatoryBowelDiseases=3
Glioma=3
KidneyDiseases=1
DiabetesMellitus=1
CrohnDisease=1
rs2228226 C
rs2076753 chr16 50699463 (GRCh38.p13) G>A / G>T NOD2 Intron Variant CrohnDisease=3
Colitis_Ulcerative=2
Uveitis=2
PulmonaryDisease_ChronicObstructive=2
Arthritis_Psoriatic=2
rs2076753 C
rs2067085 chr16 50699948 (GRCh38.p13) C>A / C>G NOD2 Synonymous Variant Colitis_Ulcerative=3
CrohnDisease=3
Uveitis=3
Meningitis=2
PulmonaryDisease_ChronicObstructive=2
rs2067085 C
rs2066842 chr16 50710713 (GRCh38.p13) C>A / C>T NOD2 Missense Variant ParkinsonDisease=26
CrohnDisease=21
Neoplasms=21
Uveitis=11
Colitis_Ulcerative=7
rs2066842 A
rs2066843 chr16 50711288 (GRCh38.p13) C>A / C>T NOD2 Synonymous Variant CrohnDisease=16
Colitis_Ulcerative=6
Uveitis=4
PulmonaryDisease_ChronicObstructive=3
Arthritis_Psoriatic=3
rs2066843 B
rs1861759 chr16 50711672 (GRCh38.p13) T>G NOD2 Synonymous Variant Arthritis_Psoriatic=5
CrohnDisease=4
Uveitis=4
Sarcoidosis=4
Colitis_Ulcerative=3
rs1861759 C
rs5743291 chr16 50723365 (GRCh38.p13) G>A NOD2 Missense Variant CrohnDisease=5
Uveitis=4
Sarcoidosis=4
Colitis_Ulcerative=3
PulmonaryDisease_ChronicObstructive=3
rs5743291 A
rs1077861 chr16 50725636 (GRCh38.p13) A>C / A>T NOD2 Intron Variant Asthma=6
CrohnDisease=2
Colitis_Ulcerative=1
Uveitis=1
PulmonaryDisease_ChronicObstructive=1
rs1077861 C
rs2277680 chr17 4735268 (GRCh38.p13) G>A CXCL16 Missense Variant HepatitisB=7
CrohnDisease=2
LiverFailure_Acute=2
HamartomaSyndrome_Multiple=1
InflammatoryBowelDiseases=1
rs2277680 C
rs3894326 chr19 5843773 (GRCh38.p13) A>C / A>T FUT3 Missense Variant GeneticDiseases_Inborn=4
LungDiseases=3
Colitis=1
HeredodegenerativeDisorders_NervousSystem=1
IgADeficiency=1
C
rs28362459 chr19 5844781 (GRCh38.p13) A>C / A>G / A>T FUT3 Missense Variant GeneticDiseases_Inborn=4
Colitis=4
LungDiseases=3
HeredodegenerativeDisorders_NervousSystem=2
CoronaryDisease=1
C
rs280519 chr19 10362257 (GRCh38.p13) A>C / A>G TYK2 Intron Variant LupusErythematosus_Systemic=16
Colitis_Ulcerative=4
HepatitisC_Chronic=3
Sarcoma=3
BreastNeoplasms=3
C
rs280523 chr19 10366530 (GRCh38.p13) G>A / G>C TYK2 Synonymous Variant Endometriosis=2
Infertility=2
CrohnDisease=1
Colitis_Ulcerative=1
Inflammation=1
rs280523 C
rs1545620 chr19 17192965 (GRCh38.p13) T>A / T>C / T>G MYO9B Missense Variant CrohnDisease=5
Colitis_Ulcerative=3
InflammatoryBowelDiseases=3
Isobutyryl_CoADehydrogenaseDeficiency=2
HamartomaSyndrome_Multiple=2
rs1545620 B
rs492602 chr19 48703160 (GRCh38.p13) A>G / A>T FUT2 Synonymous Variant||LOC105447645|Non Coding Transcript Variant CrohnDisease=5
Neoplasms=3
Psoriasis=2
Adenoma=1
PancreaticNeoplasms=1
rs492602 C
rs601338 chr19 48703417 (GRCh38.p13) G>A FUT2 Stop Gained||LOC105447645|Non Coding Transcript Variant Infections=64
InflammatoryBowelDiseases=29
CrohnDisease=22
CeliacDisease=22
DiabetesMellitus=18
rs601338 A
rs1883832 chr20 46118343 (GRCh38.p13) T>A / T>C / T>G CD40 Non Coding Transcript Variant LupusErythematosus_Systemic=59
GravesDisease=55
Atherosclerosis=42
Arthritis_Rheumatoid=39
AcuteCoronarySyndrome=31
C
rs1801198 chr22 30615623 (GRCh38.p13) G>A / G>C TCN2 Missense Variant Neoplasms=18
AutisticDisorder=14
SpinalDysraphism=9
Carcinoma_SquamousCellOfHeadAndNeck=6
BreastNeoplasms=6
C
rs6622126 chrX 106956972 (GRCh38.p13) G>A MORC4 Missense Variant ZellwegerSyndrome=3
CrohnDisease=1
rs6622126 C

Identified Disease Ontologies based on the extracted SNPs

Statistics

Identified SNPs in the three major Groups

Identified SNPs in the Category A

Identified SNPs in the Category B

Identified SNPs in the Category C

GWAS Analysis Results

Identified SNPs in Human Chromosomes

Identified SNPs, Genes and Promoters per Chromosomes

Semantic and Datamining of identified Genes


Identified GenesConnected GenesRelative Publications
TNFRSF1B TNF 11607787 ,15280569 ,16306881 ,19684152
TNFRSF1B HLA-DRB1 11607787
TNFRSF1B STAT4 19684152
TNFRSF1B TNFRSF8 16306881
TNFRSF1B TNFRSF1A 15280569
TNFRSF1B TNFRSF14 16306881
IL23R IL10 23054011 ,25369137
IL23R ICAM1 23054011
IL23R CCR7 24699314
IL23R CCL5 24699314
IL23R IL12A 24699314
IL23R STAT4 20454450 ,25369137
IL23R IL5 23054011
IL23R ISG20 23054011
IL23R JAK2 23054011
IL23R S1PR1 23054011
IL23R IL2RA 22174698
IL23R LIG3 22174698
IL23R OLIG3 22174698
IL23R TNFSF4 22174698 ,24699314
IL23R VTCN1 22174698
IL23R IRAK1 25369137
IL23R MIR146A 25369137
IL23R PSORS1C1 25369137
IL23R PTPN2 25369137 ,24699314
IL23R IL4 24699314
IL23R INS 24699314
IL23R IRF5 24699314
IL23R MIF 24699314
IL23R MS4A1 24699314
IL23R PTGS1 24699314
IL23R PTPN22 24699314
IL23R RETN 24699314
IL23R SELE 24699314
IL23R TNFRSF11B 24699314
IL23R ERAP1 25369137
IL23R CD40LG 23054011
IL23R IL17RE 23054011
IL23R ATG16L1 25369137
IL23R HCP5 25369137
IL23R ADIPOQ 24699314
IL23R CDKN2B 24699314
IL23R CSF1 24699314
PTPN22 C2 15883854 ,19440199 ,20483040
PTPN22 C5 21968398
PTPN22 PSS 16163373 ,15933742 ,31616406
PTPN22 CRP 16519819 ,20947557
PTPN22 CR2 32607330
PTPN22 CD4 21542789 ,28237724 ,31616406
PTPN22 IL4 24699314
PTPN22 CD28 26092158
PTPN22 CD22 31616406
PTPN22 CD40 21542789 ,31616406
PTPN22 HLA-DRB1 17932559 ,20234359
PTPN22 FYN 16052172
PTPN22 LCK 16052172
PTPN22 BCR 22236425 ,29251774 ,30540579 ,31616406
PTPN22 LYN 20947557
PTPN22 MAF 16519819
PTPN22 PSC 18065500
PTPN22 CTLA4 20962850 ,19507500 ,21792837 ,24653663
PTPN22 NAT2 20035223
PTPN22 CSK 16052172 ,15734872 ,15620463 ,19299707
PTPN22 APCS 29040339
PTPN22 FCGR2A 18204446 ,21792837
PTPN22 INS 16519819 ,24699314
PTPN22 NOS3 32607330
PTPN22 IL1B 28786745
PTPN22 IL1RN 16519819
PTPN22 HLA-DRA 31032751
PTPN22 IRF5 16964481 ,17158136 ,19440199 ,21060334 ,20947557 ,20131239 ,20962850 ,20035223 ,18438842 ,19796918 ,18204446 ,21794545 ,24699314 ,26092158 ,24653663 ,31032751
PTPN22 PDCD1 16964481 ,17021721 ,16052172 ,15883854 ,19440199 ,20947557 ,21792837
PTPN22 TRIO 17158136 ,18065500
PTPN22 SRC 16052172 ,15620463 ,18056643
PTPN22 STAT1 17932559
PTPN22 STAT4 17932559 ,19440199 ,21060334 ,20947557 ,20131239 ,20035223 ,19796918 ,18204446 ,19714582 ,29783350 ,21968398 ,21792837 ,21542789 ,24653663 ,31032751 ,30920455
PTPN22 TCF7 15620463
PTPN22 SLC22A4 15883854
PTPN22 RUNX1 16519819
PTPN22 SLC9A3R1 16519819
PTPN22 SPINK5 16519819
PTPN22 SPP1 19440199
PTPN22 TNFAIP3 19440199 ,21060334 ,20947557 ,21542789 ,26092158 ,26683155 ,31032751
PTPN22 TNFSF4 19440199 ,21060334 ,20962850 ,21792837 ,24699314 ,24587899 ,31032751
PTPN22 PXK 20947557 ,18204446 ,19714582 ,21792837
PTPN22 XKR6 20947557 ,20962850
PTPN22 UBE2L3 20962850
PTPN22 TYK2 20035223 ,19714582
PTPN22 SH2B3 19956107
PTPN22 TLR7 19956107 ,29251774
PTPN22 TLR8 19956107
PTPN22 UBASH3A 19956107
PTPN22 SLC24A3 20483040
PTPN22 RHD 21384170
PTPN22 RAF1 21968398
PTPN22 TRAF1 21968398
PTPN22 RETN 24699314
PTPN22 SELE 24699314
PTPN22 TNFRSF11B 24699314
PTPN22 TNIP1 24587899 ,31032751
PTPN22 UHRF1BP1 24587899
PTPN22 REM2 26683155
PTPN22 TREM2 26683155
PTPN22 TNF 19440199 ,21060334 ,20947557 ,20962850 ,21792837 ,21542789 ,24699314 ,26092158 ,24587899 ,26683155 ,28527290 ,31032751
PTPN22 VDR 28527290
PTPN22 TLR4 29251774
PTPN22 TLR9 29251774 ,30540579 ,31616406
PTPN22 TNXB 31032751
PTPN22 TRPV4 32607330
PTPN22 PTPRC 31616406
PTPN22 PTPRO 31616406
PTPN22 SYK 31616406
PTPN22 MBL2 21792837
PTPN22 NFKB1 16519819
PTPN22 CCR7 24699314
PTPN22 IRAK1 20947557
PTPN22 CCL5 24699314
PTPN22 PADI4 17968335 ,17932559 ,15883854 ,16519819 ,20234359
PTPN22 CFH 16519819
PTPN22 ADAM33 16519819
PTPN22 FCRL3 17932559 ,16519819 ,18065500 ,20234359
PTPN22 LAG3 16519819
PTPN22 BTK 31616406
PTPN22 BANK1 19440199 ,21060334 ,20947557 ,20962850 ,19714582 ,21792837
PTPN22 BLK 19440199 ,21060334 ,20947557 ,20131239 ,26092158 ,24587899 ,31032751
PTPN22 ITGAM 19440199 ,21060334 ,20947557 ,20035223 ,18204446 ,19714582 ,21792837 ,24587899 ,31032751
PTPN22 MTOR 30920455
PTPN22 AK1 20947557
PTPN22 ATG5 20947557
PTPN22 MECP2 19714582 ,21792837
PTPN22 LY9 19714582
PTPN22 IL2RA 26092158
PTPN22 FAM167A 20131239
PTPN22 ERBB3 20962850 ,19956107
PTPN22 ICA1 20962850
PTPN22 CLEC16A 19956107
PTPN22 FHOD3 19956107
PTPN22 IL12A 24699314
PTPN22 LRP1B 20483040 ,28785369
PTPN22 CFB 21792837
PTPN22 PTPN2 16964481 ,17021721 ,16868974 ,17092257 ,16052563 ,18075792 ,17158136 ,15641066 ,15999805 ,17066073 ,15273934 ,15759012 ,16163373 ,16052172 ,15732281 ,17968335 ,17932559 ,16464986 ,17868256 ,16697661 ,16320352 ,15933742 ,17259401 ,16391555 ,16185328 ,15934099 ,17729039 ,15734872 ,16760194 ,15620463 ,15986374 ,15719322 ,15883854 ,16519819 ,18056643 ,18065500 ,16273109 ,19440199 ,21060334 ,20739780 ,20947557 ,21078766 ,19210878 ,19028372 ,20131239 ,20962850 ,20035223 ,18981062 ,19956107 ,18438842 ,20965855 ,19796918 ,20483040 ,18204446 ,19714582 ,29783350 ,19507500 ,21794545 ,20234359 ,18194365 ,21190368 ,19299707 ,21818561 ,23314521 ,23966601 ,21384170 ,21968398 ,22704547 ,23950893 ,24269925 ,21543514 ,21792837 ,21542789 ,23076337 ,24189282 ,22204900 ,21467606 ,23619366 ,22236425 ,21515266 ,25463433 ,24699314 ,26013387 ,24433447 ,26092158 ,26018863 ,26748951 ,27166176 ,24985973 ,26077719 ,24653663 ,24587899 ,25003765 ,26683155 ,25523449 ,24188455 ,28619073 ,28785369 ,28527290 ,28990435 ,29729713 ,29251774 ,30886958 ,29512901 ,28786745 ,28237724 ,29040339 ,30540579 ,31032751 ,30871426 ,32607330 ,31232672 ,31616406 ,30871019 ,30920455 ,30507064
PTPN22 MIF 21794545 ,24699314
PTPN22 KIF5A 26092158
PTPN22 NLRP3 28786745
PTPN22 MSH5 21792837
PTPN22 CARD11 31032751
PTPN22 PRM1 21542789
PTPN22 ADIPOQ 24699314
PTPN22 CDKN2B 24699314
PTPN22 CSF1 24699314
PTPN22 MS4A1 24699314
PTPN22 PTGS1 24699314
PTPN22 HLA-DRB4 25523449
PTPN22 PTPN11 31616406
PTPN22 COL2A1 32607330
ECM1 CAMP 32201411
ECM1 FN1 29439094
ECM1 TIMP4 29439094
ECM1 IGF1 32201411
ECM1 IGF2 32201411
ECM1 PGR 32201411
ECM1 PRLR 32201411
ECM1 PTGER2 32201411
ECM1 PTGER4 32201411
ECM1 PTGES 32201411
TLR5 SSB 26689915
TLR5 CYP1A1 26689915
TLR5 MIA 19474110
TLR5 STAT4 26689915
TLR5 IL1RN 31396542
TLR5 TLR3 18373699 ,26592511 ,26762473 ,31396542
TLR5 LY6E 18373699
TLR5 IRF5 26221343
TLR5 MYD88 26592511 ,26221343
TLR5 CXCL8 31396542
TLR5 TLR2 18373699 ,19474110 ,26592511 ,31396542
TLR5 TLR4 18373699 ,19474110 ,20952467 ,26762473
TLR5 TLR9 17516623 ,18373699 ,26762473 ,26221343
TLR5 TLR7 19473567 ,18373699 ,19474110 ,26592511 ,26762473
TLR5 TLR8 18373699 ,26762473
TLR5 TNFSF10 26352601
TLR5 TXN 26352601
TLR5 TYMS 26689915
TLR5 TRAF6 26221343
TLR5 CX3CR1 26352601
TLR5 TIA1 26352601
TLR5 ESR1 26689915
TLR5 SIGIRR 31396542
TLR5 MTRR 26689915
TLR5 COMT 26689915
TLR5 PRF1 26352601
TLR5 PRKCH 26352601
TLR5 LY96 26352601
TLR5 SLC19A1 26689915
TLR5 IL1RAP 31396542
TLR5 IL18R1 31396542
IMPDH2 CTPS1 23506439
IMPDH2 TRAP 26274951
IMPDH2 KLF2 32415749
IMPDH2 LTB 32415749
IMPDH2 IMPDH1 26274951
IMPDH2 HPRT1 32415749
ERAP1 KIF5A 19110536
ERAP1 PIP4K2C 19110536
ERAP1 TNFAIP3 19110536
ERAP1 HCP5 25369137
ERAP1 IL10 25369137
ERAP1 IRAK1 25369137
ERAP1 MIR146A 25369137
ERAP1 PSORS1C1 25369137
ERAP1 PTPN2 25369137
ERAP1 STAT4 25369137
ERAP1 ATG7 24582332
ERAP1 ATG16L1 25369137
ERAP2 PIK3C3 20671926
SLC22A4 CTLA4 15829243
SLC22A4 PDCD1 15829243 ,15883854
SLC22A4 RUNX1 16249223 ,15184985 ,15829243
SLC22A4 SUMO4 16249223
SLC22A4 SLC9A3R1 15829243
SLC22A4 DLG5 15829243
SLC22A4 PADI4 15829243 ,15883854
SLC22A4 ADAM33 15829243
SLC22A4 DPP10 15829243
SLC22A4 PHF11 15829243
IRGM IL10 21300624
IRGM IL12B 21300624
IRGM ATG5 21622776
IRGM IL1R2 21300624
IRGM ATG7 21622776
IRGM JAK2 21300624
IRGM LAMB1 21300624
IRGM NOD2 21300624
IRGM ORMDL3 21300624
IRGM PRDM1 21300624
IRGM REL 21300624
IRGM SMAD3 21300624
IRGM TYK2 21300624
IRGM ATG16L1 21300624
IRGM CARD9 21300624
IRGM CDH1 21300624
IRGM ICOSLG 21300624
HLA-DQA2 GC 23257407
HLA-DQA2 HLA-DQA1 23257407
HLA-DQA2 HLA-DQB1 23257407
HLA-DQA2 HLA-DRB1 23257407
HLA-DQA2 RB1 23257407
NOD1 NOD2 23352252
ABCB1 PGP 18820766
ABCB1 UGT1A7 20567810 ,24548980
ABCB1 UGT2B7 20567810 ,24548980
ABCB1 MAX 22380717
ABCB1 BCR 25156507
ABCB1 STS 25156507
ABCB1 SYK 25156507
ABCB1 ABCC2 24548980
ABCB1 ABCG2 24548980
ABCB1 CYP2B6 24548980
ABCB1 CYP2C9 24548980
ABCB1 CYP3A4 24548980
ABCB1 UGT1A9 24548980
ABCB1 CYP3A5 28324194
DEFB1 IV 30236992
TNFSF15 CXCL1 32042744
TNFSF15 CXCL11 32042744
TNFSF15 CCT 29803925
TNFSF15 IL19 32042744
CARD9 ATG16L1 21300624
CARD9 CDH1 21300624
CARD9 ICOSLG 21300624
CARD9 IL10 21300624
CARD9 IL12B 21300624
CARD9 IL1R2 21300624
CARD9 JAK2 21300624
CARD9 LAMB1 21300624
CARD9 NOD2 21300624
CARD9 ORMDL3 21300624
CARD9 PRDM1 21300624
CARD9 REL 21300624
CARD9 SMAD3 21300624
CARD9 TYK2 21300624
CARD9 CD36 28130494
CARD9 IL1A 28130494
CARD9 IL1B 28130494
CARD9 NLRP3 28130494
CARD9 TLR4 28130494
PRKCQ C5 20049410
PRKCQ CD40 20049410
PRKCQ IRF5 20049410
PRKCQ CCL21 20049410
PRKCQ IL21 20049410
PRKCQ CDK6 20049410
PRKCQ IL2RB 20049410
PRKCQ KIF5A 20049410
PRKCQ KLF12 20049410
PRKCQ MMEL1 20049410
PRKCQ RAF1 20049410
PRKCQ STAT4 20049410
PRKCQ TNFAIP3 20049410
PRKCQ TRAF1 20049410
DLG5 CTLA4 15829243
DLG5 IBD5 16642031
DLG5 NOD2 16642031
DLG5 DPP10 15829243
DLG5 PADI4 15829243
DLG5 PDCD1 15829243
DLG5 PHF11 15829243
DLG5 RUNX1 15829243
DLG5 SLC9A3R1 15829243
DLG5 ADAM33 15829243
TNFRSF1A C2 18174230
TNFRSF1A C3 18174230
TNFRSF1A SHE 24835548
TNFRSF1A CR2 18174230
TNFRSF1A TNF 15280569 ,15492850 ,16216134 ,18174230 ,24835548 ,25684197
TNFRSF1A CD28 18174230
TNFRSF1A CD22 18174230
TNFRSF1A FYN 18174230
TNFRSF1A LYN 18174230
TNFRSF1A CD19 18174230
TNFRSF1A CTLA4 18174230
TNFRSF1A TGFB1 18174230
TNFRSF1A APCS 18174230
TNFRSF1A DNASE1 18174230
TNFRSF1A C1QA 18174230
TNFRSF1A C1QB 18174230
TNFRSF1A ICOS 18174230
TNFRSF1A IFNG 18174230
TNFRSF1A PDCD1 18174230
TNFRSF1A MBL2 18174230
TNFRSF1A F5 18174230
TNFRSF1A CDKN1A 18174230
TNFRSF1A F13B 18174230
TNFRSF1A FADD 18174230
TNFRSF1A TNFRSF4 18174230
TNFRSF1A TNFSF10 18174230
TNFRSF1A TNFSF11 18174230
TNFRSF1A TNFSF12 18174230
TNFRSF1A TNFSF13B 18174230
TNFRSF1A TNFSF4 18174230
TNFRSF1A TRADD 18174230
TNFRSF1A FLI1 18174230
TNFRSF1A PTEN 18174230
TNFRSF1A TNFAIP3 25684197
TNFRSF1A F10 18174230
TNFRSF1A F11 18174230
TNFRSF1A F12 18174230
TNFRSF1A IGHM 18174230
TNFRSF1A MAN2A1 18174230
TNFRSF1A MERTK 18174230
TNFRSF1A PTPN6 18174230
TNFRSF1A PTPRC 18174230
TNFRSF1A TGFB2 18174230
TNFRSF1A TGFB3 18174230
TNFRSF1A TGFBR1 18174230
TNFRSF1A TGFBR2 18174230
TNFRSF1A TGFBR3 18174230
TNFRSF1A TNFRSF11A 18174230
TNFRSF1A TNFRSF11B 18174230
TNFRSF1A MEFV 24835548
LRRK2 C3 30670047
NOD2 IV 31186034
NOD2 CTLA4 19567624
NOD2 IL10 21300624 ,25652333
NOD2 JAK2 21300624
NOD2 FCGR2A 19567624
NOD2 IRF5 19567624 ,22412986
NOD2 IL12B 21300624
NOD2 IBD5 16642031
NOD2 PDCD1 19567624
NOD2 TYK2 19567624 ,21300624 ,25652333
NOD2 ORMDL3 21300624
NOD2 PRDM1 21300624
NOD2 REL 21300624
NOD2 SMAD3 21300624
NOD2 TRAF6 22412986
NOD2 PTPN2 25652333
NOD2 TNFSF4 25652333
NOD2 UNC13D 32222431
NOD2 NFKBIA 32222431
NOD2 NLRP3 31186034
NOD2 IL1R2 21300624
NOD2 ATG16L1 21300624
NOD2 CDH1 21300624
NOD2 ICOSLG 21300624
NOD2 LAMB1 21300624
NOD2 CSF2 25652333
NOD2 CSF1 25652333
NOD2 NLRC5 31186034
NOD2 DNASE2 32222431
CXCL16 C3 30006918
CXCL16 CCR5 18187931
CXCL16 CXCL10 18187931
CXCL16 TNF 17982109
CXCL16 CXCL9 18187931
CXCL16 CXCR3 18187931
CXCL16 EBI3 18187931
CXCL16 IV 22788914
CXCL16 FABP2 31019506
CXCL16 LBP 31019506
CXCL16 CCL5 18187931
CXCL16 CCL4 18187931
CXCL16 CXCL11 18187931
TYK2 SSB 30777133
TYK2 GC 30740104
TYK2 SYK 29108825
TYK2 CTLA4 19567624 ,19758313
TYK2 NAT2 20035223
TYK2 NCF2 22046141
TYK2 IL10 21300624 ,25652333
TYK2 STAT1 21179067 ,29475858 ,31130957
TYK2 REL 21300624
TYK2 JAK2 21300624 ,29475858 ,30621465
TYK2 STAT4 19442287 ,20035223 ,21179067 ,19714582 ,29475858
TYK2 FCGR2A 19567624
TYK2 SMAD3 21300624
TYK2 MX1 30772492
TYK2 IRF5 15657875 ,19567624 ,20035223 ,21179067 ,19758313 ,26294277
TYK2 PDCD1 19567624
TYK2 TNFSF4 25652333
TYK2 MYD88 29108825
TYK2 IFI27 30772492
TYK2 IL12B 21300624
TYK2 IFIH1 22046141 ,30171347
TYK2 BANK1 19442287 ,19714582
TYK2 ITGAM 19442287 ,20035223 ,19714582
TYK2 PXK 19442287 ,19714582
TYK2 IKZF1 22046141
TYK2 MECP2 19442287 ,19714582
TYK2 LY9 19442287 ,19714582
TYK2 SOCS1 22859983 ,31130957
TYK2 IKBKE 21179067
TYK2 TANK 21179067
TYK2 TRAF6 21179067
TYK2 IRAK4 29108825
TYK2 PRDM1 21300624
TYK2 PTPN2 20035223 ,19714582 ,25652333
TYK2 DLK1 19966805
TYK2 STAT2 22859983
TYK2 IL1R2 21300624
TYK2 IRF8 22046141
TYK2 IFI6 30772492
TYK2 JAK1 22859983 ,31130957 ,30621465
TYK2 ATG16L1 21300624
TYK2 CDH1 21300624
TYK2 ICOSLG 21300624
TYK2 LAMB1 21300624
TYK2 ORMDL3 21300624
TYK2 CSF2 25652333
TYK2 CSF1 25652333
TYK2 JAK3 30621465
TYK2 IKZF2 29059182
TYK2 CERS5 30777133
TYK2 ETV7 30777133
TYK2 ITGB1 30777133
TYK2 KRT7 30777133
TYK2 SLC13A3 30777133
TYK2 DNAJA1 30772492
TYK2 IFIT5 30772492
CD40 C2 32576231 ,29763203
CD40 C3 18706081 ,23799000 ,29763203
CD40 C5 11772239 ,27713252 ,20049410 ,29763203
CD40 C4A 32576231
CD40 C1R 32576231
CD40 C1S 32576231
CD40 ALB 9550377 ,12969144 ,16507174 ,16849443 ,16008514 ,25886192
CD40 CD4 9309192 ,8683147 ,9802931 ,9884095 ,9696135 ,9617563 ,9708833 ,8621796 ,9498753 ,9884096 ,9008608 ,9884104 ,9550377 ,9036998 ,9671306 ,8892665 ,11123036 ,12139375 ,11987985 ,11086109 ,11226290 ,10510335 ,10342716 ,11438470 ,11086108 ,11772239 ,12727626 ,10933611 ,11737595 ,11764210 ,11751941 ,12390309 ,11243513 ,12730502 ,12584053 ,11721699 ,11905840 ,12855571 ,12969144 ,16507174 ,18061155 ,17884785 ,16483919 ,15989801 ,15230296 ,16640741 ,17432112 ,16849443 ,16670339 ,17530637 ,17947713 ,17579090 ,15657613 ,15583738 ,15742155 ,14994397 ,15564715 ,15701725 ,15951839 ,15621569 ,16008514 ,15693003 ,15494542 ,15613107 ,14979930 ,15599672 ,16971957 ,15491417 ,21159836 ,19812195 ,18706081 ,20478074 ,20067533 ,20811042 ,18684674 ,19854711 ,20810985 ,19520616 ,18180380 ,19758160 ,20112371 ,20855873 ,27713252 ,20049410 ,18285351 ,19644874 ,19549767 ,20130210 ,22110533 ,22113625 ,23340289 ,22385876 ,22142890 ,23054011 ,22580585 ,23933625 ,21415255 ,22952582 ,21262968 ,21914625 ,22343096 ,23029299 ,22147767 ,23680362 ,23576011 ,23434382 ,22577035 ,23256180 ,21542789 ,22870484 ,22184503 ,23799000 ,24036458 ,22951828 ,21255096 ,22860133 ,21538324 ,21429584 ,23181381 ,24374810 ,22936933 ,21799861 ,27816669 ,24480124 ,26209442 ,26867643 ,26289938 ,27001848 ,25201689 ,27102765 ,26474561 ,27069113 ,27752154 ,26968426 ,27722794 ,27509492 ,26335795 ,25886192 ,27585815 ,26432891 ,27665947 ,25381385 ,25789080 ,24482685 ,26140268 ,25309746 ,27852746 ,25640675 ,28421990 ,29175653 ,30374748 ,29330524 ,30113724 ,29127458 ,29040209 ,29214033 ,31165780 ,30774014 ,32249615 ,31642196 ,31217170 ,31109957 ,32942031 ,32675278 ,32890026 ,31616406 ,32161059 ,32576231 ,29763203 ,31831255
CD40 CD2 8892665 ,11086109 ,11086108 ,17432112 ,15494542 ,27713252 ,23680362 ,21255096 ,21799861 ,27722794 ,32675278 ,31616406 ,32576231
CD40 CD28 8892665 ,11086108 ,15494542 ,23680362 ,32576231
CD40 CD22 11086109 ,17432112 ,27713252 ,21799861 ,27722794 ,32675278 ,31616406
CD40 APC 11123036 ,11086108 ,12727626 ,15951839 ,15494542 ,20130210 ,24374810 ,31109957
CD40 CD80 9309192 ,11123036 ,11751941 ,16507174 ,15989801 ,15951839 ,21159836 ,18706081 ,20067533 ,21415255 ,23680362 ,24036458 ,21429584 ,26867643 ,25789080 ,26140268 ,32576231
CD40 FAS 9309192 ,12855571
CD40 CD69 9696135 ,12139375 ,15693003
CD40 IV 9008608 ,12730502 ,29127458 ,29040209
CD40 CD86 11123036 ,11751941 ,16507174 ,17530637 ,17579090 ,19812195 ,18706081 ,20478074 ,20067533 ,18684674 ,19854711 ,20810985 ,19644874 ,22147767 ,23680362 ,22577035 ,24036458 ,21429584 ,26867643 ,27509492 ,27585815 ,25381385 ,25789080 ,24482685 ,32576231
CD40 POLE 11086109
CD40 TH 11086108 ,12727626 ,15491417
CD40 CD68 12730502 ,17579090
CD40 TES 12584053
CD40 PRL 11721699
CD40 SF 11905840 ,20478074 ,29214033
CD40 MR1 12969144
CD40 TAM 18061155
CD40 CD83 15989801 ,17579090 ,18706081 ,21429584
CD40 CXCL8 17579090
CD40 TNF 15657613 ,15701725 ,20112371 ,27713252 ,20049410 ,22385876 ,23933625 ,22343096 ,21542789 ,22870484 ,24480124 ,25640675 ,29330524 ,29214033 ,31217170 ,32576231
CD40 GC 15564715 ,22951828 ,27069113 ,32161059
CD40 CD5 15701725 ,22184503
CD40 ELL 16008514
CD40 CD44 15494542
CD40 JUN 14979930
CD40 CRP 15599672
CD40 VWF 15599672
CD40 CXCR3 15491417 ,23434382 ,27001848
CD40 MPO 15491417
CD40 ICOS 21159836 ,23680362 ,22870484
CD40 PDC 19812195 ,20478074 ,18684674 ,27509492
CD40 TLR9 19812195 ,18684674 ,19758160 ,27509492 ,25309746 ,31616406
CD40 FLT3 20478074
CD40 TLR7 18684674 ,20112371 ,27509492 ,25309746
CD40 MYD88 20112371
CD40 SIGIRR 20112371
CD40 CDK6 20049410
CD40 IL21 20049410
CD40 IL2RB 20049410
CD40 IRF5 20049410 ,29214033
CD40 KIF5A 20049410
CD40 KLF12 20049410
CD40 MMEL1 20049410
CD40 RAF1 20049410 ,21262968
CD40 STAT4 20049410 ,21542789
CD40 TNFAIP3 20049410 ,21542789 ,31217170
CD40 TRAF1 20049410 ,21262968
CD40 SERPINB2 20130210
CD40 CD70 23340289 ,22142890 ,23029299 ,22184503
CD40 ITGAL 23340289 ,22142890 ,23029299 ,22184503
CD40 PRF1 23340289 ,23029299 ,22184503
CD40 RFX1 23340289
CD40 SRY 22580585
CD40 GAPDH 21415255
CD40 TRAF6 21262968 ,22860133
CD40 PRM1 21542789
CD40 CTLA4 23799000
CD40 TLR4 24036458 ,25309746
CD40 CD84 21255096
CD40 IDE 21255096 ,29175653
CD40 TRAF3 22860133
CD40 MCM6 21538324
CD40 HOXC4 23181381
CD40 STAT3 24374810 ,26968426
CD40 TG 23340289 ,22142890 ,23029299 ,22184503 ,21799861
CD40 FOXO1 27816669
CD40 TIGIT 26867643
CD40 STAT1 26968426
CD40 CD63 27665947
CD40 CXCR4 27665947
CD40 EBF1 25789080
CD40 NM 23029299 ,22184503 ,24482685
CD40 TLR3 25309746
CD40 UBE2L3 25640675
CD40 TNFSF4 29214033
CD40 XBP1 32249615
CD40 EGFR 31642196
CD40 CR2 31217170
CD40 IL10 23054011 ,31217170 ,32576231
CD40 STS 32675278
CD40 SYK 32675278 ,31616406
CD40 MET 32890026
CD40 PSS 31616406
CD40 PTPN11 31616406
CD40 PTPN2 21542789 ,31616406
CD40 PTPRC 31616406
CD40 PTPRO 31616406
CD40 FH 32161059
CD40 CD40LG 17947713 ,19520616 ,22142890 ,23054011 ,23029299 ,23576011 ,23434382 ,22184503 ,27001848 ,29040209 ,32576231
CD40 ELANE 32576231
CD40 H2AX 32576231
CD40 MACROH2A2 32576231
CD40 PIK3CB 32576231
CD40 TRIM21 32576231
CD40 RAG1 29763203
CD40 RAG2 29763203
CD40 CAD 15599672
CD40 BCR 15742155 ,15701725 ,23181381 ,27816669 ,32675278 ,31616406 ,32161059 ,32576231
CD40 CD19 11086109 ,32890026
CD40 CD36 21415255 ,21255096
CD40 CD14 17579090 ,19854711 ,20855873
CD40 CCR5 19854711
CD40 APCS 11123036 ,15951839 ,20130210 ,31109957
CD40 CCL2 17579090 ,20049410
CD40 CCL22 17579090
CD40 C1QA 32576231
CD40 CBL 11086108 ,23434382
CD40 CD1A 15989801 ,17579090
CD40 CCR7 20478074 ,18684674 ,19854711 ,21429584
CD40 CCL19 19854711
CD40 CCL21 20049410
CD40 BTK 32890026 ,31616406
CD40 BANK1 27816669
CD40 BCL6 27665947
CD40 CD226 27722794
CD40 CD33 21255096
CD40 CD37 21255096
CD40 AICDA 23181381


Extracted Genes from Data mining analysis in Graph

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SNPs analysis results for SLE      

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Data mining analysis results for SLE     

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Publications that has been used in Data mining analysis

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Current SLE related Genes in Graph

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Current SLE related SNPs in Chromosomes

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SLE accosiated Genes in Graph         

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SLE accosiated SNPs in Chromosomes

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